Work

Pregabalin dependence: Experiences from liaison psychiatric settings in Kashmir, North India: A case series

Year: 2025

Type: article

Abstract: Pregabalin, a gamma-aminobutyric acid (GABA) analog, is a new-generation antiepileptic that is approved for the treatment of neuropathic pain, fibromyalgia, partial seizures, and generalized anxiety disorder. There is a rising concern regarding its abuse potential, and a handful of case reports have highlighted the same. We present a case series on pregabalin dependence. In contrast to previous case reports, which focused on patients with a history of illicit drug abuse, we present cases of drug-naïve individuals for whom pregabalin was the first substance of abuse. The highlight of the study is that we describe cases of pregabalin intoxication and a rare case of pregabalin withdrawal, which presented as a lethal suicidal attempt to liaison psychiatric settings.

Source: Industrial Psychiatry Journal

DOI: 10.4103/ipj.ipj_474_24

Authors: Aaliya Khanam, Rajnish Raj, Zaid A. Wani, Yasir H. Rather, Iqra Arshad

Institution: Government Medical College

Language: English

Topic: Opioid Use Disorder Treatment

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $60