Work

In silico identification and experimental validation of long-range allosteric inhibition of Staphylococcus aureus Cas9 catalytic activity by an anti-CRISPR protein AcrIIA14

Year: 2025

Type: article

Source: International Journal of Biological Macromolecules

DOI: 10.1016/j.ijbiomac.2025.143324

Authors: Jiacheng Wei, Feiying Chen, Xun Lu, Jigang Fan, Mingyu Li, Jianxiang Huang, Ning Liu, Jian Zhang, Zongtao Chai, Shaoyong Lu

Institutions: Shanghai Jiao Tong University, Ningxia Medical University, Shanghai Medical College of Fudan University, Fudan University, Zhongshan Hospital

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: National Natural Science Foundation of China, National Key Research and Development Program of China

Awards: G1317052866, G1657543646, G2919143877

OpenAlex ID: W4409577094

FWCI: 3.275

Cites: 77

Cited by: 13

Related to: 10