Disparities in Colorectal Cancer Incidence Trends Among Hispanics Living in Puerto Rico (2000–2021): A Comparison With Surveillance, Epidemiology, and End Results (SEER) Database
Year: 2025
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Although the overall colorectal cancer (CRC) incidence has been steadily declining in the United States, a dramatic increase in the number of CRC cases among individuals younger than 50 years of age (early-onset CRC) has been observed. CRC is the second and first leading cause of cancer death in the United States and among Hispanic men and women living in Puerto Rico (PRH), respectively. We report CRC incidence rates from 2000 to 2021 among PRH and compare them to data in the Surveillance, Epidemiology, and End Results Program (SEER). METHODS: Data on colorectal adenocarcinomas diagnosed between January 1, 2000, and December 31, 2021, were obtained from the Puerto Rico Central Cancer Registry and SEER17, including race and ethnicity. Age-standardized incidence rates were calculated using the direct method. The Joinpoint Regression Program calculated temporal trends on CRC incidence rates based on age-adjusted Average Annual Percent Change (AAPC) estimates. RESULTS: A total of 729,479 incident cases of CRC were analyzed. US Hispanics had the highest percentage of early-onset CRC (EOCRC) cases (17.0%) among the racial and ethnic groups studied. PRH had the highest age-standardized EOCRC incidence rate (12.18 per 100,000 persons) and the highest increase in EOCRC incidence temporal trends (AAPC = 2.68; 95% CI: 1.83 to 3.51). CONCLUSIONS: A significantly higher increase in EOCRC incidence was observed among Hispanic populations. Future studies should disaggregate Hispanic subpopulations by considering the country of ancestral origin, which will help identify specific risk factors and exposures and aid in developing tailored prevention and risk stratification strategies to reduce EOCRC incidence.
Source: Cancer Medicine
DOI: 10.1002/cam4.70851
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $4,700
Awards: G1060873854, PUERTO RICO CANCER PREVENTION AND CONTROL PROGRAM AND COORDINATING CENTER - PUERTO RICO-CANCER CONTROL COORDINATING CENTER THIS NOFO WILL ALLOW THE PUERTO RICO BREAST AND CERVICAL CANCER EARLY DETECTION PROGRAM (PRBCCEDP) TO CONTINUE ITS EFFORTS PROMOTING THE BENEFITS OF BREAST AND CERVICAL CANCER SCREENING AND PROVIDING SCREENING AND DIAGNOSTIC SERVICES TO THE UNINSURED AND UNDERINSURED WOMEN. THE GOALS AND OBJECTIVES OF THE PRBCCEDP ARE IN ALIGNMENT WITH THOSE OF THE PRCCC PLAN, THE PUERTO RICO CHRONIC DISEASE PREVENTION AND HEALTH PROMOTION PLAN, PUERTO RICO HEALTHY PEOPLE 2030, AND CDC’S DIVISION OF CANCER PREVENTION AND CONTROL PROGRAMS, AND OTHER NATIONAL AND LOCAL ORGANIZATIONS. THE NEXT FUNDING CYCLE (2022-2027) IS TO “SUPPORT HIGH-QUALITY BREAST AND CERVICAL CANCER SCREENING SERVICES” THROUGH THE IMPLEMENTATION OF POLICY, SYSTEMS, AND ENVIRONMENTAL CHANGE STRATEGIES TO REACH THE LONG-TERM GOAL OF REDUCING BREAST AND CERVICAL CANCER MORBIDITY, MORTALITY, AND RELATED DISPARITIES.” THIS NOFO WILL ALLOW THE PUERTO RICO COMPREHENSIVE CANCER CONTROL PROGRAM (PRCCCP) TO MAINTAIN LEADERSHIP IN THE COORDINATION OF CANCER CONTROL EFFORTS ON THE ISLAND. THE PROGRAM COMPLIES WITH THE MANDATE OF LAW 49 OF THE GOVERNMENT OF PUERTO RICO (APRIL L 8, 2011) FOR PUBLIC POLICY OF THE GOVERNMENT OF PUERTO RICO FOR COMPREHENSIVE CANCER CONTROL”; TO SUPPORT THE PUERTO RICO CANCER CONTROL COALITION (PRCCC), AND TO CONTINUE SUPPORTING AND PROMOTING THE IMPLEMENTATION OF THE PUERTO RICO COMPREHENSIVE CANCER CONTROL PLAN. NCCCP PRIORITY AREAS FOR THE PERIOD 2022-2027 ARE PRIMARY PREVENTION OF CANCER; CANCER EARLY DETECTION EFFORTS; CANCER SURVIVORS’ NEEDS; HEALTH EQUITY THROUGH THE IMPLEMENTATION OF ENVIRONMENTAL APPROACHES FOR SUSTAINABLE CANCER CONTROL; AND HEALTH SYSTEMS INTERVENTIONS. THE PRCCCP WILL INCREASE COLLABORATION ACROSS CDC’S CANCER PREVENTION AND CONTROL PROGRAMS AND OTHER CHRONIC DISEASE CONTROL PROGRAMS; INCREASE AND MAINTAIN PARTNERSHIPS; USE CANCER-RELATED SURVEILLANCE DATA; AND MONITOR AND EVALUATION OF THE PROGRAM IMPACT. THE PUERTO RICO CENTRAL CANCER REGISTRY (PRCCR) PROPOSED PROJECT INCLUDES ACTIVITIES UNDER STRATEGIES 1, 2, 3, AND 5 AS REQUIRED IN THIS NOFO. THE OPERATIONAL PLAN DESCRIBES TWO MAIN GOALS: 1) TO CONTINUE TO IMPROVE AND SUSTAIN CASE FINDING, COMPLETENESS, TIMELINESS, AND QUALITY THAT MEETS NPCR’S NATIONAL DATA QUALITY STANDARDS AND ADVANCED NATIONAL DATA QUALITY STANDARDS (GOALS 1-5). DATA FILES SUBMITTED TO NPCR-CSS WILL MEET CRITERIA FOR PUBLICATION IN THE UNITED STATES CANCER STATISTICS (GOAL 6); AND 2) TIMELY DISSEMINATION OF HIGH-QUALITY DATA IN SUPPORT OF PUBLIC HEALTH CANCER PREVENTION AND CONTROL EFFORTS BY STATE, LOCAL INSTITUTIONS, AND COMMUNITY ORGANIZATIONS AND EVALUATE CANCER PREVENTION AND SCREENING PROGRAMS (GOAL 7). THE OVERARCHING GOAL FOR THE 5-YEAR PERIOD IS TO FULFILL THE NATIONAL DATA QUALITY STANDARD (24-MONTH STANDARD) AND HAVE AT LEAST 95% OF DATA COMPLETE ANNUALLY AND TO HAVE AT LEAST 60% DATA COMPLETE OF THE ADVANCED NATIONAL DATA QUALITY STANDARD (12-MONTH STANDARD) BY THE END OF THE 5-YEAR PERIOD (CURRENTLY 36%)., G4856677802, Center for the Promotion of Cancer Health Equity (CePCHE)
OpenAlex ID: W4409591874