Year: 2025
Type: article
Study design: Case Report
Abstract: Sarcoidosis is a multi-system granulomatous disease of unknown etiology that can present with various systemic symptoms and laboratory abnormalities, including hypercalcemia. This case report describes a 74-year-old male who presented with hypercalcemia, weight loss, fatigue, and low-grade fevers, initially raising concern for malignancy. A lymph node biopsy revealed non-caseating granulomas consistent with sarcoidosis. Elevated angiotensin-converting enzyme (ACE) levels further supported the diagnosis. This case highlights the importance of considering sarcoidosis in the differential diagnosis of hypercalcemia and systemic symptoms, especially in elderly patients with complex medical histories.
Source: Cureus
DOI: 10.7759/cureus.82649
Institution: Zayed Military Hospital
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409608696