Designing atomically precise gold nanocluster architectures with DNA-guided self-assembly and biofunctionalization approaches
Year: 2025
Type: article
Abstract: -which emit in the NIR-I (600-800 nm) and NIR-II (900-1300 nm) spectral windows, respectively. These biofunctionalized AuNCs, which can be considered nanomolecular building blocks, were thoroughly characterized using complementary analytical and optical techniques, including absorption and fluorescence spectroscopy, mass spectrometry, liquid chromatography, and gel electrophoresis. Through selective DNA hybridization, we successfully assembled AuNC dimers, trimers, and AuNC-dye nanosystems with high reproducibilities and yields. This work lays the foundation for the design of AuNC-DNA superstructures with potential applications in optoelectronics, sensing, and nanomedicine.
Source: Nanoscale
DOI: 10.1039/d5nr00905g
Institutions: Centre National de la Recherche Scientifique, Inserm, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, CEA Grenoble, Institut pour l'avancée des biosciences, Systèmes Moléculaires et nanoMatériaux pour l'Énergie et la Santé, Université Grenoble Alpes, Institut de Biologie Structurale, Institut de Recherche Interdisciplinaire de Grenoble
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: hybrid
Awards: G1064512522, CBH-EUR-GS, G1817966306, G1825864493, G2277544366, G2447855386, G256544642, G2659019386, G2911514573, G4460985483, Decorating Disordered Proteins with Gold NanoClusters: Synthesis, Structure and Molecular Sensing Capabilities, Development of the next generation of Swir emItting pRobEs for bioimaging, G6803667113, G6891474181, G7240651115, G796440745, G8305889996, G8548513469
OpenAlex ID: W4409619415