Silent Thyroiditis Presented as Transient Hypothyroidism During Pregnancy: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Silent thyroiditis during pregnancy is an under-recognized clinical condition and arare case, often manifesting as transient hypothyroidism. We report a 23-year-oldwoman at 8 weeks of gestation who presented with newly diagnosed hypothyroidism[TSH = 85 mIU/L (0.4–4.5), FT4 = 0.4 ng/dL (0.7–2.5), and anti-TPO = 78 IU/mL (upto 16)]. Thyroid function tests had been normal eight months prior. Levothyroxine(LT4) therapy was initiated, restoring euthyroidism. Treatment was discontinuedpostpartum, and the patient maintained normal thyroid function for over one year.Our case is unique in that silent thyroiditis occurred unusually early in pregnancyand differed from the more common postpartum cases. Silent thyroiditis should beconsidered in pregnancy-related hypothyroidism, particularly when prior thyroidfunction was normal. Prompt diagnosis and treatment can prevent adverse maternaland fetal outcomes
Authors: Mahmoud Ali Kaykhaei, Shahin Nosratzehi
Institution: Zahedan University of Medical Sciences
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409623229