Work

Abstract 2909: Targeting Polθ suppresses CCNE1-amplified cancers via transcription-replication conflicts mediated DNA damage and RAD51 toxicity

Year: 2025

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2025-2909

Authors: Chuancong Zhu, Yu Xu, Xuejiao Zhao, Gordon B. Mills, Ding Ma, Qinglei Gao, Yong Fang

Institutions: Tongji Hospital, Huazhong University of Science and Technology, Oregon Health & Science University, OHSU Knight Cancer Institute

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4409627412

Cites:

Cited by: 1

Related to: 10