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Abstract 2996: TNG462, an MTA-cooperative PRMT5 inhibitor, demonstrates strong efficacy in combination with clinically relevant targeted therapies in MTAP-null preclinical models

Year: 2025

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2025-2996

Authors: Minjie Zhang, Alice Tsai, Kevin M. Cottrell, Brian B. Haines, Alan Huang, Jannik N. Andersen, Adam S. Crystal, Kimberly J. Briggs

Institution: Tango Therapeutics (United States)

Language: English

Topic: Cancer-related gene regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4409627569

Cites:

Cited by: 5

Related to: 10