Work

Late Relapse After Autologous Hematopoietic Stem Cell Transplantation in AQP4-IgG–Positive NMOSD

Year: 2025

Type: article

Study design: Case Report

Abstract: This case series examines long-term outcomes for 2 aquaporin-4-IgG (AQP4-IgG)–positive patients with neuromyelitis optica spectrum disorder (NMOSD) who underwent autologous hematopoietic stem cell transplantation with a nonmyeloablative conditioning regimen and rituximab.

Source: JAMA Network Open

DOI: 10.1001/jamanetworkopen.2025.5989

Authors: Nisa Vorasoot, Kyle M. Blackburn, Linda Nguyen, Melissa L. Bush, Sarah M. Jenkins, Jiraporn Jitprapaikulsan, James P. Fryer, Sarosh R. Irani, Eoin P. Flanagan, Sean J. Pittock

Institutions: Mayo Clinic, Khon Kaen University, The University of Texas Southwestern Medical Center, Siriraj Hospital, Mahidol University, Mayo Clinic in Florida

Language: English

Topic: Multiple Sclerosis Research Studies

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,000

Funders: Wellcome Trust, National Institute for Health and Care Research, Medical Research Council

Award: The immunobiology of autoantibody-mediated diseases of the central nervous system.

OpenAlex ID: W4409628426

FWCI: 2.393

Cites: 6

Cited by: 4

Related to: 10