Work

Abstract 4309: Loss of the tumor suppressor NUMB is a hallmark of biologically and clinically aggressive bladder cancer and leads to hyperactivation of an actionable RHOA-ROCK-YAP circuitry

Year: 2025

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2025-4309

Authors: Francesco A. Tucci, Maria Grazia Filippone, Roberta Bonfanti, Elisa Guerrera, Luca Acerbi, Giuseppe Renne, Gianluca Vago, Daniela Tosoni, Salvatore Pece

Institutions: European Institute of Oncology, University of Milan

Language: English

Topic: Hippo pathway signaling and YAP/TAZ

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4409628920

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