Work

Exclusive human milk diet is associated with lower risk of motor function impairment at three years of corrected age

Year: 2025

Type: article

Abstract: OBJECTIVES: To evaluate the association between an exclusive human milk diet (EHMD) and motor function impairment at three years of corrected age among infants born before 32 weeks of gestation. METHODS: We conducted a retrospective study between 2018 and 2021. We assigned to the EHMD group infants who received an EHMD for ≥75% of the days between the first day of diet fortification and 33 6/7 weeks postmenstrual age. We used inverse propensity scores to balance potential confounders and developed a mixed-effects logistic regression model to assess the association. RESULTS: After adjusting for demographics and morbidities, an EHMD was associated with a reduced risk of motor function impairment, with an odds ratio of 0.74 (95% CI: 0.56-0.98, p = 0.036). CONCLUSIONS: An EHMD is associated with a decrease in the odds of early childhood motor function impairment among infants born before 32 weeks of gestation.

Source: Journal of Perinatology

DOI: 10.1038/s41372-025-02296-z

Authors: Fu-Sheng Chou, Jing Zhang, Maria Fe B. Villosis, Ashwini Lakshmanan

Institutions: Kaiser Permanente, Kaiser Permanente Riverside Medical Center, Kaiser Permanente Bernard J. Tyson School of Medicine

Language: English

Topic: Infant Development and Preterm Care

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: hybrid

Estimated APC paid: $4,790