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Abstract 5607: Discovery and preclinical evaluation of a potent, orally bioavailable, highly selective, small molecule PTPN2/1 inhibitor

Year: 2025

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2025-5607

Authors: Alexei Pushechnikov, Vladislav Parchinsky, Aleksei Riakhovskii, Stepan Mochalov, Ruben Karapetian, Amy Burd, Nikolay Savchuk, Iain Dukes, Ruben Abagyan

Institutions: ChemDiv (United States), Molsoft (United States)

Language: English

Topic: Protein Tyrosine Phosphatases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4409631124

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