Natural Deep Eutectic Solvents for the Extraction of Mulberroside A from White Mulberry Root Bark
Year: 2025
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide In this study, an ultrasonic extraction method of mulberroside A from Morus alba L. based on natural deep eutectic solvents (NADESs) was developed. A total of 24 natural deep eutectic solvents (NADESs) with different formulations were designed to extract M. alba L. powder, and high-performance liquid chromatography (HPLC) was used as the detection method, with the content of mulberroside A as the only evaluation index. The results showed that malic acid:glucose (1:3) contained the highest mulberroside A content of 0.06% with excellent extraction specificity. In addition, the parameters such as water content, extraction temperature, extraction time, and feed/liquid ratio, which have a great influence on NADESs, were optimized, and the antioxidant activity of NADES extracts was tested. Finally, further fine separation of mulberroside A by semidynamic adsorption on porous polymer beads yielded a refined product of mulberroside A under NADES extraction conditions with a purity of 82.9%.
Source: ACS Omega
Authors: Zhiyang Chen, Zhengyou He, Jialan Qin
Institution: Chengdu University
Language: English
Subfield: Catalysis
Field: Chemical Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,935
Award: G7321953303
OpenAlex ID: W4409633687