Work

Abstract 5512: Combining RAS(ON) G12C-selective and RAS(ON) multi-selective inhibitors overcomes sotorasib resistance driven byKRASG12C amplification or NRASG13R mutation

Year: 2025

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2025-5512

Authors: Hitendra Singh Solanki, Denis Imbody, Bina Desai, Daria Miroshnychenko, Bhaswati Sarcar, Anurima Majumder, Yonghong Zhang, Uwe Rix, Andriy Marusyk, Mallika Singh, Ida Aronchik, Eric B. Haura

Institutions: Moffitt Cancer Center, Revolution Medicines (United States)

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4409634038

Cites:

Cited by: 1

Related to: 10