Ultrastructural organization of the epithelial lining of the vascular bodies of the lateral ventricles of the brain.
Year: 2025
Type: article
Abstract: Changes in the composition of the cerebrospinal fluid can lead to the development of diseases of the nervous system. To understand their pathogenesis, clear data on the morphology of vascular bodies, especially their epithelial lining, is needed. Considering these circumstances, the aim of the study was to determine the peculiarity of the ultrathin organization of epitheliocytes of the vascular bodies of the lateral ventricles of the brain. For the study, fragments of vascular plexus tissues from three adult Bos taurus specimens were used, which were selected during routine slaughter. The processing of the selected samples for the production of ultrathin sections was carried out in accordance with the generally accepted methodology. The sections were contrasted in 2.0% aqueous solution of uranyl acetic acid and lead citric acid. The study of the obtained sections in order to determine the features of the ultrathin structure of vascular epitheliocytes was carried out using a Jem – 1011 electron microscope. When specifying the terms, we were guided by the International Histological Nomenclature. It has been established that epithelial cells of vascular bodies have morphological features characteristic of synthesizing cells. These include the presence of a light nuclear matrix, indicating a high level of synthetic activity, as well as the presence of structures that enlarge the membrane surface, represented by its protrusions in the form of apical microvilli and invaginations forming a basal labyrinth.
Author: A. V. Prusakov
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4409646212