Work

Evidence for the involvement of secondary bile acids on peripheral and central regulation of feed intake in rainbow trout

Year: 2025

Type: article

Abstract: This study determined for the first time in teleost fish (specifically in rainbow trout): 1) the role of secondary bile acids in the regulation of feed intake and associated signaling pathways, highlighting a putative orexigenic role of lithocholic acid (LCA); 2) the response of Asbt and Ostα transporters and Tgr5 receptor in hypothalamus after LCA administration; and 3) the reabsorption of LCA, DCA, and their taurine conjugates from the gastrointestinal tract into the bloodstream.

Source: American Journal of Physiology-Endocrinology and Metabolism

DOI: 10.1152/ajpendo.00072.2025

Authors: Gabriel Pérez-Tierra, Jessica Calo, Sara Comesaña, Cristina Velasco, Ayelén M. Blanco, José L. Soengas

Institution: Universidade de Vigo

Language: English

Topic: Aquaculture Nutrition and Growth

Subfield: Aquatic Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: hybrid

Funder: Agencia Estatal de Investigación

Awards: G438772562, G4988987420, G5487000844