IMPLEMENTATION OF THE TARGETED SYNTHESIS OF 6-SUBSTITUTED-4 AMINO-7H-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS
Year: 2025
Type: article
Abstract: 7H-Pyrrolo[2,3-d]pyrimidines or 7-deazapurines are analogs of purines, which are part of DNA and RNA found in the human body, and therefore exhibit a high level of biological activity. There are also several approved drugs containing the 7H-pyrrolo[2,3 d]pyrimidine nucleus, and most of them are used as Janus kinase inhibitors. This research work focuses on the synthesis of targeted compounds using molecular docking.
Authors: Sh. Gaybullayev, A. Nasrullayev, R. Kuryazov, H.A. Aisa, N. Chao, Kh.Bozorov Bozorov
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W4409648449