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Aortic Endocarditis on Bicuspid Valve Complicated by Valvular Perforation and Severe Aortic Regurgitation due to Methicillin-resistant Staphylococcus aureus: A Case Report

Year: 2025

Type: article

Abstract: Infective endocarditis (IE) on a bicuspid aortic valve (BAV) is a severe condition associated with high morbidity and mortality rates despite diagnostic and therapeutic advances. We report the case of a 25-year-old patient admitted with prolonged fever, exertional dyspnea, and marked asthenia, who was diagnosed with complicated aortic endocarditis. Echocardiography revealed a type 0 bicuspid valve with perforation of the anterior cusp, leading to severe aortic regurgitation. Serial blood cultures identified methicillin-resistant Staphylococcus aureus (MRSA). Intravenous vancomycin therapy was urgently initiated, followed by aortic valve replacement with a mechanical prosthesis. The postoperative course was favorable, with complete resolution of the infectious syndrome and proper prosthetic function. This case highlights the importance of early diagnosis and prompt medical-surgical management in the face of severe complications of IE on BAV.

DOI: 10.9734/ajcr/2025/v8i1266

Authors: Yamoul Jihane, Kaoutar Mouammine, Rachida Habbal

Institution: Centre Hospitalier Universitaire Ibn Rochd

Language: English

Topic: Infective Endocarditis Diagnosis and Management

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4409650002

FWCI:

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