Work

Influence of Pre-existing Diabetes Mellitus on Executive Function Deficits in Adult Traumatic Brain Injury

Year: 2025

Type: article

Abstract: BACKGROUND: The study aims to examine the compounded effects of pre-existing diabetes mellitus (DM) on executive functions (EFs) in young and middle-aged adults with traumatic brain injury (TBI). METHODS: We conducted a cross-sectional analysis involving 97 individuals divided into 3 groups: adults with TBI, adults with both TBI and DM, and a healthy control group. We assessed the participants using various neuropsychological tests and functional status questionnaires. RESULTS: The study found that participants with both TBI and DM exhibited significantly worse outcomes on measures of EF than those with TBI alone. Additionally, patients with TBI and a history of DM perceived a greater need for assistance with cognitive and emotional issues. CONCLUSIONS: These findings underscore the need for integrated care strategies that specifically cater to the heightened neuropsychological impairments in young and middle-aged adults with TBI and DM. Future research should continue to explore these relationships longitudinally to understand and address the long-term impacts of combined TBI and DM on EFs within this age group.

Source: World Neurosurgery

DOI: 10.1016/j.wneu.2025.123999

Authors: Bei-Yi Su, Tee-Tau Eric Nyam, Che-Chuan Wang, Hsin-Fan Wang, Jinn-Rung Kuo

Institutions: Chung Shan Medical University Hospital, Chung Shan Medical University, Chi Mei Medical Center, Kuang Tien General Hospital, National Sun Yat-sen University

Language: English

Topic: Traumatic Brain Injury Research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,943