Work

Portable electrophoretic lateral flow biosensing for ultra-sensitive human lactate dehydrogenase detection in serum samples

Year: 2025

Type: article

Abstract: for human lactate dehydrogenase (h-LDH), a key cancer biomarker, using gold nanoparticles as signal transducers. This result means a 367-fold improvement in sensitivity. Offering rapid, cost-effective, and ultra-sensitive biomarker quantification, this approach holds significant promise for transforming precision medicine, particularly in monitoring LDH-related cancer therapies.

Source: Biosensors and Bioelectronics

DOI: 10.1016/j.bios.2025.117504

Authors: Amadeo Sena-Torralba, Yulieth D. Banguera-Ordoñez, Javier Carrascosa, Ángel Maquieira, Sergi Morais

Institutions: Universitat de València, Universitat Politècnica de València, Sociedad de Doctores e Investigadores de Colombia, Instituto de Investigación Sanitaria La Fe

Language: English

Topic: Biosensors and Analytical Detection

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,540