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Prostaglandins limit nuclear actin rod formation during Drosophila oogenesis

Year: 2025

Type: article

Abstract: oogenesis. Loss of prostaglandin (PG) synthesis and signaling results in an increased frequency of cells with nuclear actin rods; there are less rods per cell, but the rods are longer. These findings suggest that loss of PGs results in increased nuclear actin and are consistent with prior findings assessing the roles of PGs in modulating endogenous nuclear actin. Thus, GFP-Actin rod formation can be used as a tool to screen for new regulators of nuclear actin.

Source: PubMed

DOI: 10.17912/micropub.biology.001571

Author: Tina L. Tootle

Institution: University of Iowa

Language: English

Topic: Cellular Mechanics and Interactions

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4409653389

FWCI:

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