Polydopamine-assisted dual metal ion modification of titanium: Enhancing osseointegration and antibacterial performance
Year: 2025
Type: article
Abstract: being continuously and stably released in liquid environments. Additionally, TPDA@CuCa significantly improved protein adsorption, facilitating favorable cellular interactions. In vitro experiments demonstrated that TPDA@CuCa exhibited strong antimicrobial activity against Escherichia coli and Staphylococcus aureus, enhanced osteoblast adhesion, mineralization, and upregulated osteogenic gene expression. This bifunctional surface modification strategy offers a promising approach to enhancing both the osteogenic and antibacterial properties of Ti implants.
Authors: Jingyang Kang, Sikun Meng, Chenhui Liu, Huachun Wang, Tianzhen Zhang, Cheng Qi, Mei Li
Institutions: Shandong University, The University of Osaka
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $3,790
Award: G7714505690
OpenAlex ID: W4409657112