Work

Evaluating an electronic patient-reported outcome monitoring system in patients with prostate cancer in routine clinical care: a prospective observational study

Year: 2025

Type: article

Abstract: PURPOSE: This study evaluated the feasibility, acceptability, and clinical utility of an electronic patient-reported outcome (ePRO) system for patients undergoing radiation therapy (RT) for prostate cancer in routine clinical practice. METHODS: A prospective observational study was conducted at the Medical University of Innsbruck among patients receiving RT for primary or recurrent prostate cancer. The ePRO system was designed to capture patient-reported symptoms and health-related quality of life throughout treatment and follow-up, aiming to standardize symptom monitoring and improve continuity of care. Patients completed questionnaires at baseline, during treatment, and in follow-up with feasibility defined as ≥ 75% of patients completing at least 75% of scheduled assessments. Patients' acceptability was evaluated at baseline and at treatment end using self-developed questionnaires. Healthcare professionals' (HCPs) perception of clinical utility of the system was measured with a self-developed questionnaire. RESULTS: Forty patients participated in the study with a median age of 71 years. The ePRO system was feasible, with an average completion rate of 87%, exceeding the feasibility threshold. Patient acceptability was high, with 98% (39/40) expressing willingness to use it regularly. HCPs' feedback was also positive, with all HCPs (100%, 8/8) reporting usefulness of the system in clinical care and 83% reporting that the system helped them in the clinical assessment of their patients. CONCLUSION: The ePRO monitoring system was feasible and well-accepted among both patients and HCPs, demonstrating potential for continued use in routine clinical care. Further efforts are needed to optimize clinical integration and address barriers to ensure equitable access.

Source: Quality of Life Research

DOI: 10.1007/s11136-025-03977-0