Regulation of perinatal estrogen levels on primordial follicle formation and activation in mouse
Year: 2025
Type: article
Abstract: In this study, the roles and underlying mechanisms of perinatal estrogen level changes in primordial follicle formation and activation in mice were elucidated. The elevated estrogen levels before birth inhibited the premature formation of primordial follicles and enhanced the quality of oocyte differentiation. Conversely, the reduced estrogen levels following birth promoted the activation of primordial follicles.
Authors: Rui Xu, Lu Yin, Yiqian Zhang, Yinxiang Niu, Sihai Lu, Yaju Tang, Sha Peng, Menghao Pan, Baohua Ma
Institution: Northwest A&F University
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Award: G38174529
OpenAlex ID: W4409665249