Work

A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis

Year: 2025

Type: article

Abstract: This case is notable for the potential overlap of hereditary alpha tryptasemia and eosinophilic granulomatosis with polyangiitis. The successful use of mepolizumab, initially for eosinophilic granulomatosis with polyangiitis but potentially benefiting the patient's hereditary alpha tryptasemia, offers a novel approach to managing complex cases involving both rare disorders.

Source: Journal of Allergy and Clinical Immunology Global

DOI: 10.1016/j.jacig.2025.100481

Authors: Sonia Iqbal, Joseph A. Baxter, Karla E. Adams

Institutions: Malcolm Grow Medical Clinic, Wilford Hall Ambulatory Surgical Center

Language: English

Topic: Mast cells and histamine

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,000