Work

Indirect, but not direct, lateral habenula projections to ventral tegmental area regulate the long-term consequences of neuropathic pain

Year: 2025

Type: article

Abstract: Chronic pain, in which pain persists or recurs for more than 3 months, is a major cause of suffering and disability worldwide. Chronic pain caused by an insult to the somatosensory nervous system is known as neuropathic pain. Individuals affected by prolonged neuropathic pain often experience cognitive and emotional disturbances such as pain catastrophizing, anxiety, depressive symptoms, and fear or avoidance of movement and injury [ 1 ].

Source: Neuropsychopharmacology

DOI: 10.1038/s41386-025-02111-5

Authors: Emily D. Prévost, David H. Root

Institution: University of Colorado Boulder

Language: English

Topic: Pain Mechanisms and Treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,290