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Hirata Disease (Insulin Autoimmune Syndrome)- A Rare Disease Manifesting as Hypoglycemia

Year: 2025
Type: article
Abstract: Insulin autoantibodies at high titres cause hypo-glycemia episodes in patients with insulin autoimmune syndrome, commonly known as Hirata's disease. Immuno-absorbent syndrome is a type of immune-mediated hypoglycaemia that arises when a trigger such as a drug or a virus interacts with a predisposed genetic background. Insulin-Auto antibodies complexes are formed during the pathophysiology of Insulin Autoimmune Syndrome and cause double-phase glycaemic changes. Insulin is released from the complexes regardless of blood glucose concentrations, causing hypoglycaemia.
Language: English
Subfield: Genetics
Open Access status: diamond
OpenAlex ID: W4409680357
FWCI: 0.552
Cites:
Cited by: 1
Related to: 10