Year: 2025
Type: article
Abstract: NTRK (neurotrophic tyrosine receptor kinase) gene fusions are genetic alterations that can drive cancer development, including in lung cancer.The incidence of neurotrophic myosin receptor kinase (NTRK) fusions in NSCLC is extremely low, with reports of approximately 0.2%.By reviewing the literature, we will learn about the NTRK gene family, the distribution of NTRK fusions in tumors, its detection methods, the treatment and resistance mechanism of targeted drugs, so that clinicians can have a deeper understanding of NTRK fusion lung cancer.
Source: Research Review
Author: Cunhua Yuan
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409689410