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Abstract 498: In melanoma, disruption of the NF1/SPRED1 RAS inactivating complex cooperates with mutant KIT necessitating combined KIT and MEK inhibition to suppress tumor growth

Year: 2025

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2025-498

Authors: Meng Kian Tee, Jia Yang, Jiafang Ma, Meng Wang, Dirk Schadendorf, Boris C. Bastian, Iwei Yeh

Institutions: University of California, San Francisco, Essen University Hospital, Deutsches Konsortium für Translationale Krebsforschung

Language: English

Topic: Melanoma and MAPK Pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4409690454

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