Work

Blood cancer driven by ‘one hit’ mutation event undergoes rapid growth

Year: 2025

Type: article

Abstract: Reconstructions of the ‘evolutionary’ relationships among blood-cell clones from individuals with the blood cancer chronic myeloid leukaemia reveal that the cancer clone grows exceptionally quickly, reaching rates of between 10,000% and 1,000,000% per year. This variability in growth rate could explain differences in responses to cancer treatments. Variability in the growth rate of chronic myeloid leukaemia could contribute to differences in treatment response among patients.

Source: Nature

DOI: 10.1038/d41586-025-01170-4

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $12,690

OpenAlex ID: W4409698112

FWCI:

Cites: 4

Cited by:

Related to: 10