Work

Genomic comparative analysis of Enterobacter asburiae harbouring a conjugative blaIMI−6-plasmid isolated from a public garden in Switzerland

Year: 2025

Type: article

Abstract: Ambler class A IMI enzymes are minor carbapenemases primarily associated with the Enterobacter cloacae complex. Screening soil surfaces of a well-visited public garden revealed an IMI-6-producing Enterobacter asburiae ST657 near a trash can. The strain harboured a 163-kb conjugative IncFII(Yp) plasmid containing bla IMI−6 and putative virulence genes. WGS comparative analysis with other clinical and non-clinical E. asburiae ST657 showed that it was genetically related to strains from a patient in France (62 ΔSNPs) and from retail salad in Switzerland (79 ΔSNPs). This finding suggests possible trans-sectoral dissemination of IMI-producing bacteria raising concerns since they could further spread into the community.

Source: European Journal of Clinical Microbiology & Infectious Diseases

DOI: 10.1007/s10096-025-05131-7

Authors: Yvonne Spahr, Andrea Endimiani, Vincent Perreten

Institution: University of Bern

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,890