Year: 2025
Type: article
Abstract: Sulfate-reducing bacteria (SRB) are a major cause of microbially-induced corrosion (MIC) and souring (MIS), leading to significant challenges in industries like oil recovery and wastewater treatment. Due to SRB's resistance to antimicrobial agents, bacteriophage (phage) therapy offers a promising alternative for SRB control. In this study, a novel lytic phage, SRB7757, targeting Desulfovibrio vulgaris, was isolated from sewage. SRB7757 inhibited sulfide production by 92.3% within 24 h and significantly reduced corrosion on metal specimens after 28 days, highlighting its potential in controlling MIC and MIS. Genome analysis revealed SRB7757 has a genome size of 142,573 bp, 217 ORFs, and 6 tRNAs, and belongs to the Chaseviridae family. SRB7757 exhibits a latent period of 4 h, a burst size of ~ 100 PFU/cell, and is stable between 4 °C and 60 °C across a pH range of 2.0-12.0. Two predicted lytic enzymes of SRB7757 demonstrated higher inactivation and biofilm removal rates.
Source: BMC Microbiology
Authors: Guangming Zhang, Zisheng Guo, Shuo Liu, Qiaoli Yang, Yiming Yuan, Ke Guo, Weixiao Wang, Haina Wang, Jie Feng, Wei Chen, Yanmei Sun, Shiwei Wang
Language: English
Subfield: Ecology
Field: Environmental Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,990
OpenAlex ID: W4409703538