Work

Discovery of Carbodiimide Warheads to Selectively and Covalently Target Aspartic Acid in KRASG12D

Year: 2025

Type: article

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.5c03562

Authors: Ludovica S. Sirocchi, Maximilian Scharnweber, Sarah Oberndorfer, Gabriella Siszler, Krzysztof M. Zak, Klaus Rumpel, Ralph A. Neumüller, Birgit Wilding

Institution: Boehringer Ingelheim (Austria)

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

OpenAlex ID: W4409720294

FWCI: 3.788

Cites: 40

Cited by: 15

Related to: 10