Work

Isolated Posterior Mitral Valve Cleft Diagnosed by 3D Echocardiography in an Elderly Woman

Year: 2025

Type: article

Abstract: BACKGROUND: Isolated posterior mitral valve cleft (MVC) is a rare congenital anomaly that can be easily overlooked with standard 2-dimensional imaging. CASE SUMMARY: A 94-year-old woman with progressive heart failure symptoms was found to have severe mitral regurgitation due to an isolated posterior MVC. Three-dimensional echocardiography provided detailed visualization of the lesion's anatomy and confirmed the diagnosis. After excluding a percutaneous repair due to the cleft's complexity, she underwent minimally invasive surgical repair, resulting in substantial symptomatic improvement. DISCUSSION: Posterior MVCs are infrequently reported and often missed by conventional imaging. Advances in 3-dimensional echocardiography have enhanced diagnostic accuracy, guiding targeted interventions. This case shows the importance of comprehensive imaging for such rare anomalies and the feasibility of surgical repair, even in elderly patients.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2025.103367

Authors: Adam M. Khalil, Nadya Almatrooshi, Umer Darr, Aiman Smer, Mohammed E. Khalil

Institutions: Weill Cornell Medical College in Qatar, Weill Cornell Medicine, Cleveland Clinic Abu Dhabi

Language: English

Topic: Cardiac Valve Diseases and Treatments

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $850