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Villiform cardiac myxoma with atypical glandular differentiation in a young girl: a case report

Year: 2025

Type: article

Abstract: BACKGROUND: Cardiac myxoma with glandular differentiation is a rare finding. It accounts for approximately ≤ 3% of all cardiac myxomas. The presence of cellular atypia resembling adenocarcinoma is an extremely rare finding in cardiac myxoma. CASE PRESENTATION: Here, we present a case of villiform cardiac myxoma with atypical glandular differentiation in a 16-year-old Indo-Aryan girl, which was initially mistaken as metastatic adenocarcinoma on routine histology. CONCLUSION: A thorough histopathological examination, supported by immunohistochemical and radiological correlation, assists in accurate diagnosis and concurrently evades the misdiagnosis of metastatic adenocarcinoma.

Source: Journal of Medical Case Reports

DOI: 10.1186/s13256-025-05229-8

Authors: Sangram Keshari Behera, Debahuti Mohapatra, Debirupa De, Krishna Sai Sharan, Swagatika Samal

Institutions: Siksha O Anusandhan University, Institute of Medical Sciences and Sum Hospital

Language: English

Topic: Cardiac tumors and thrombi

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,890