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Sex-specific challenges in cardiovascular disease among women: gaps in recognition, diagnosis, and management

Year: 2025
Type: article
Abstract: Despite being the leading cause of mortality among women, cardiovascular disease remains underrecognized and undertreated due to sex-related differences in clinical presentation, risk factors, and healthcare delivery. Women are often excluded from clinical trials, undergo fewer diagnostic evaluations, and are less likely to receive guideline-directed therapies. Additionally, female-specific risk factors, such as pregnancy-related disorders, early menopause, and autoimmune diseases, are frequently overlooked. Addressing these disparities through sex-specific risk assessment, increased clinician awareness, and inclusion of women in research is imperative to optimize prevention and treatment strategies and reduce cardiovascular disease-related morbidity and mortality in women.
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4409741383
FWCI: 2.548
Cites: 29
Cited by: 3
Related to: 10