Year: 2025
Type: article
Abstract: Childhood psoriasis is a chronic inflammatory skin disease whose early manifestation is associated with genetic predisposition and environmental factors.Despite its growing prevalence in the pediatric population, its management still represents a clinical challenge, mainly due to the scarcity of specific therapeutic protocols and the underuse of combination therapies by pediatricians.This study consists of a narrative review of the literature, focusing on current therapeutic approaches and the psychosocial repercussions of childhood psoriasis.It showed that topical corticosteroids remain the first line of treatment, although the combination with vitamin D analogues and the use of calcineurin inhibitors show promise in terms of safety and efficacy.Resistance to the use of systemic and biological therapies reflects gaps in clinical knowledge, leading to delayed access to advanced therapies.In addition to the cutaneous manifestations, the disease has a significant psychological impact, reinforcing the need for a multidisciplinary approach centered on the child.
Authors: Ryan Rafael Barros de Macedo, Karla Leticia Santos da Silva Costa, Júlia Janot Pinheiro Procópio, Isabela Marchand Rocha Guimarães, Maricélia Lopes de Medeiros, Verônica Gabriela Souza Marques
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4409752086