Work

Optic Nerve Sheath Meningiomas in Children: Diagnostic Challenges Based on a Case Series

Year: 2025

Type: article

Abstract: The diagnosis of optic nerve sheath meningiomas (ONSM) in children and teenagers remains challenging despite advances in high-quality imaging. We identified seven children diagnosed with ONSM in four tertiary paediatric oncology centres in the United Kingdom. Our case series highlighted the value of PET-DOTATATE scans in assisting diagnosis when biopsy was considered high risk. Computed tomography (CT) scan may be useful for demonstrating calcification within the meningioma, a relatively specific finding occurring in 20%-50% of ONSM cases. Unfortunately, despite optimal treatment, vision loss is unavoidable in some patients. To improve outcomes, prompt consultation with a multidisciplinary team is recommended.

Source: Pediatric Blood & Cancer

DOI: 10.1002/pbc.31739