Year: 2025
Type: article
Study design: Case Report
Abstract: This article presents a clinical case of extramedullary plasmacytoma of the thoracic wall, which led to the development of multiple myelopathy and caused compressive spinal cord injury at the Th10 level. The clinical manifestations of the disease are described, including progressive lower spastic paraparesis with impaired pelvic organ function. A comprehensive diagnostic evaluation was conducted using neuroimaging methods (magnetic resonance imaging, computed tomography), morphological studies (soft tissue and bone marrow biopsy), and consultations with a multidisciplinary team of specialists. The patient underwent a course of radiation therapy, which contributed to partial regression of the tumor process, as well as symptomatic and neuroprotective therapy, leading to improved lower limb motor activity, reduced hypoesthesia, and restoration of bladder function. This case highlights the necessity of early diagnosis of tumors of the spine and bone marrow, as timely intervention can significantly improve the prognosis. Moreover, this clinical case underscores the importance of a multidisciplinary approach in managing patients with oncohematological pathology complicated by neurological disorders.
Institution: Danylo Halytsky Lviv National Medical University
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409761720