Work

Upregulated Lactate Dehydrogenase C4 Promotes Hepatocellular Carcinoma Progression Via Accelerating Glycolysis and Triggering the AKT/mTOR Signaling Pathway

Year: 2025

Type: article

Abstract: Lactate dehydrogenase C4 (LDHC4) plays a crucial role in regulating the interconversion between lactate and pyruvate during glucose metabolism. Yet, its expression patterns and biological roles in hepatocellular carcinoma (HCC) remain largely unknown. This study endeavors to elucidate the expression and biological function of LDHC4 in HCC.

Source: Biomedical Journal of Scientific & Technical Research

DOI: 10.26717/bjstr.2025.61.009541

Author: Zhaolei Cui Zhenzhou Xiao

Institutions: Fujian Medical University, Fujian Provincial Cancer Hospital

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Fujian Provincial Health Technology Project