Work

(3a,8b)-5-Acetyl-3a-fluoro-6,8-dihydroxy-7,8b-dimethyl-3,3a-dihydrofuro[3,2-b]benzofuran-2(8bH)-one

Year: 2025

Type: article

Abstract: Usnetic acid is a dibenzofuran-2-ylacetic acid that can be obtained by alkaline degradation of a secondary lichen metabolite—usnic acid. In the present paper, the product of the reaction of usnetic acid with a mild fluorinating agent, Selectfluor®, was obtained. The structure of the product was proved by a set of physical methods, including 1H, 13C, 19F NMR, HMBC, HSQC, HRMS and IR spectroscopy.

Source: Molbank

DOI: 10.3390/m1995

Authors: Aleksandr S. Filimonov, Stepan P. Zernov, Olga A. Luzina, Nariman F. Salakhutdinov

Institutions: Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences

Language: English

Topic: Fluorine in Organic Chemistry

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $603

Funders: Siberian Branch, Russian Academy of Sciences, Ministry of Science and Higher Education of the Russian Federation