Work

Transient Myocardial Infarction After Combined Sclerotherapy in a Lymphatic Malformation

Year: 2025

Type: article

Abstract: Bleomycin and aethoxysclerol are commonly used sclerosing agents for treating lymphatic malformations. This case report describes a serious adverse event in an infant who developed transient electrocardiogram abnormalities, tachycardia, hypotension, elevated cardiac enzymes, and reduced biventricular function after the second administration of bleomycin combined with aethoxysclerol and alcohol. These findings suggest direct cardiotoxicity, which has not been previously reported in such a young infant. This case underscores the need for close monitoring after sclerotherapy, even if no complications occur after the first treatment, and emphasizes the importance of weighing the risks and benefits of using multiple sclerosing agents in this vulnerable population.

Source: Journal of Vascular Anomalies

DOI: 10.1097/jova.0000000000000111

Authors: Daan J. Verhoeven, Manuel A. Baarslag, Ewout P. Boesaard, Marloes IJland, D. Maroeska W.M. te Loo, Bas H. Verhoeven

Institutions: Radboud University Medical Center, Rijnstate Hospital, Radboud University Nijmegen

Language: English

Topic: Vascular Malformations and Hemangiomas

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4409786481

FWCI:

Cites: 10

Cited by:

Related to: 10