Hypertensive Disorders Of Pregnancy: Exploring Epidemiology, Risk Factors, Maternal-Fetal Outcomes, And Comprehensive Management And Prevention Strategies – A Review
Year: 2025
Type: review
Abstract: Hypertensive Disorders of Pregnancy (HDPs), including gestational hypertension, preeclampsia, and chronic hypertension, are among the most significant contributors to maternal and neonatal morbidity and mortality, worldwide.These disorders affect approximately 5-10% of pregnancies globally, with variations driven by socioeconomic and healthcare disparities, particularly pronounced in low-resource settings such as rural India.Hypertensive disorders of pregnancy are associated with adverse outcomes, including placental abruption, intrauterine growth restriction, preterm birth, and long-term maternal cardiovascular and renal complications.Recent research highlighted the roles of genetic predispositions, epigenetic modifications, and gut microbiota in HDP pathophysiology, offering novel insights into prevention and management.Advances in pharmacological treatment, telemedicine integration, and personalized care strategies are improving outcomes, though gaps in global clinical guidelines and healthcare access persist.This review synthesizes the current evidence on the epidemiology, risk factors, maternal and fetal complications, and management strategies for hypertensive disorders of pregnancy, emphasizing innovative approaches to reduce their burden and promote equitable maternal and neonatal health outcomes.
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4409788863