Unraveling the evolution and global transmission of high level tigecycline resistance gene tet(X)
Year: 2025
Type: article
Abstract: , floR, sul2, tet(M) and tet(Q). Temporal changes of transfer networks of tet(X) variants, IS elements and plasmids revealed that IS elements especially ISVsa3 facilitated the expansion of tet(X). Our findings highlight the substantial transmission risk of Type-C tet(X) variants. Persistent surveillance of the global transmission and evolutionary trend of tet(X) is essential.
Source: Environment International
Authors: Chaoqun Yao, Longyang Jin, Qi Wang, Meng Wang, Ruobing Wang, Meng Cai, Kaiwen Song, Hui Wang
Institution: Peking University People's Hospital
Language: English
Subfield: Molecular Medicine
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $4,750
Awards: G4030078256, G5416988150
OpenAlex ID: W4409816869