Work

Abstract LB008: ATV-1601, a potent and selective allosteric inhibitor of AKT1E17K, demonstrates profound and durable regressions in multiple patient and cell derived xenograft models

Year: 2025

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2025-lb008

Authors: Shomit Sengupta, Aaron Coffin, Anna C. Schinzel, Christopher F. Bennett, Truc Pham, Benjamin F. Brigham, Gianna M. Iantosca, Rajiv G. Govindaraj, Joseph LaPointe, Joanne E. Prescott-Roy, William Church, Gordon Murray, Thomas Roddy, Anil K. Padyana, Marion Dorsch, Maria-Jesus Blanco

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4409821637

Cites:

Cited by: 1

Related to: 10