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Abstract CT156: Phase 1 dose-optimization study evaluating the safety of ginisortamab (UCB6114), an anti-gremlin-1 monoclonal antibody (mAb) with first-in-class potential, as monotherapy in advanced solid tumors

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Year: 2025
Type: conference-abstract
Source: Cancer Research
DOI: 10.1158/1538-7445.am2025-ct156
Authors: Debashis Sarker, Toros A. Dincman, Ruth Plummer, Udai Banerji, Natalie Cook, Heinz-Josef Lenz, Mark White, Elodie Garric, Paul Jones, Joanne Mann, Ivan Matthews, Abdul (Moe) Muhith, Sarah P. Blagden
Institutions: King's College London, Guy's and St Thomas' NHS Foundation Trust, Medical University of South Carolina, MUSC Hollings Cancer Center, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Institute of Cancer Research, University of Manchester, The Christie NHS Foundation Trust, University of Southern California, Beatson West of Scotland Cancer Centre, University of Glasgow, UCB Pharma (United Kingdom), University of Oxford, Oxford University Hospitals NHS Trust
Language: English

Topic: TGF-β signaling in diseases
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W4409821964
Cites: 1
Cited by:
Related to: 10
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