Work

Topical ruxolitinib in combination with oral minoxidil results in hair regrowth in a patient with central centrifugal cicatricial alopecia and concomitant traction alopecia

Year: 2025

Type: article

Abstract: Central centrifugal cicatricial alopecia (CCCA) is a lymphocyte-predominant scarring disorder of the scalp characterized by hair loss at the vertex or crown that expands centrifugally. This disorder disproportionately affects adult women of African descent, with an estimated prevalence of 2.5% to 5.7%.1 CCCA can significantly impact patients’ quality of life, especially when traditional treatment proves ineffective. First-line therapy for CCCA includes topical or intralesional corticosteroids and oral tetracyclines to target follicular inflammation.

Source: JAAD Case Reports

DOI: 10.1016/j.jdcr.2025.04.010

Authors: Gabriela Soto-Canetti, Hassan Hamade, Benjamin Ungar, Jordan Talia

Institution: Icahn School of Medicine at Mount Sinai

Language: English

Topic: Hair Growth and Disorders

Subfield: Urology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $750