Work

Metal–Ligand Cooperation for Iron(II)‐Catalyzed Direct Wittig‐Type Olefination from Alcohols in Air

Year: 2025

Type: article

Abstract: An iron‐catalyzed one‐pot tandem in situ oxidation–Wittig reaction is reported for the synthesis of alkenes. Using a bench‐stable Fe(II) catalyst with a redox‐noninnocent 2‐((4‐chlorophenyl)diazenyl)‐1,10‐phenanthroline ligand scaffold, a broad spectrum of substituted E olefins is synthesized in good yields by the reaction of alcohols with phosphorus ylides. Control reactions and spectroscopic studies indicate synergistic participation of the ligand, which acts as a reservoir of electrons and hydrogen, during the dehydrogenative coupling of alcohols with the phosphorus ylides.

Source: European Journal of Organic Chemistry

DOI: 10.1002/ejoc.202500257

Authors: Subhankar Khanra, Subhangi Saha, Sutanuva Mandal, Nanda Dulal Paul

Institutions: Indian Institute of Engineering Science and Technology, Shibpur, Banwarilal Bhalotia College

Language: English

Topic: Phosphorus compounds and reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: Department of Science and Technology, Ministry of Science and Technology, India, Science and Engineering Research Board

Awards: G1562348831, G6735823622