Year: 2025
Type: article
Abstract: Acne is a common chronic skin condition characterized by inflammation of the hair follicles and sebaceous glands, severely affecting patients' appearance and psychological well-being.Suitable animal models are fundamental for investigating the pathogenesis of acne and developing therapeutic strategies.This paper summarizes recent advancements in acne animal model research, exploring the construction methods of commonly used models, their advantages and limitations, and their applications in studying the pathogenesis of acne, screening drugs, and evaluating therapeutic efficacy.Additionally, recommendations for improving the design of animal models are provided to advance the field of acne research further.This review aims to offer guidance for acne vaccine research and the development of anti-inflammatory and antimicrobial drugs.
Authors: Tiannan Lu, Jing Guo, Zejun Wang
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4409829844