A case of microsporidial keratitis in an HIV-positive patient: Clinical and diagnostic insights
Year: 2024
Type: article
Study design: Case Report
Abstract: Microsporidia are small, oval, obligate intracellular eukaryotic protozoan parasites that mostly cause infections in immunocompromised individuals. The ocular manifestations include superficial punctate keratoconjunctivitis and corneal stromal keratitis. We report a case of microsporidial keratitis in an HIV patient (>500 cells/mm 3 ) successfully treated with topical voriconazole and systemic albendazole. A 50-year-old male presented with redness, watering, and pain in his left eye 1 month after failing a previous antibiotic steroid combination treatment. His best corrected visual acuity in the left eye was finger counting at 4 m and on slit lamp examination he had conjunctival congestion with a central circular corneal ulcer of about 3 mm in diameter with stromal infiltrates and anterior chamber hypopyon of about 1 mm. Microsporidial organisms were identified on corneal scraping and successfully treated for 8 weeks. The patient had complete resolution with the formation of leucomatous corneal opacity.
Source: Haryana Journal of Ophthalmology
Authors: Lalita Rani, Abhishek Sagar, Jyoti Deswal, Rajender Singh Chauhan
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4409846817